A Date with Telomerase: Pick You Up at S Phase

A date with telomerase: pick you up at S phase.

Using the MS2 system for labeling mRNA, in this issue, Gallardo et al. (2011) find that telomere lengthening depends on a stable accumulation of multiple telomerase complexes in late S phase and that this process is temporally regulated by Rif1/2 proteins.

How Do You Keep Up to Date?

Our editorial board member Philippe Kruchten has even formulated a rule of thumb—that the half-life of software engineering ideas is about fi ve years (www.computer.org/portal/web/ comput i ng now/ 0 4 09 / what snew/ software), which seems to imply a continual race to keep up with the latest ideas as the old ones become less relevant. But a generally tough economic climate seems to have made t...

Lifelong learning. Are you really up to date?

Frontline learning of medical teaching: “you pick up as you go through work and practice”

BACKGROUND Few medical teachers have received formal teaching education. Along with individual and organizational barriers to participation in teacher training programs, increasing numbers and altered distribution of physicians away from major teaching centers have increased the difficulty of attendance. Furthermore, it is not known if traditional faculty development formats are the optimal lea...

Keeping you up to date with the latest developments in your area

Does constraint-induced movement therapy improve activity and participation in children with hemiplegic cerebral palsy? Does it improve activity and participation more than the same dose of upper limb therapy without restraint? Is the effect of constraint-induced movement therapy related to the duration of intervention or the age of the children? Systematic review of randomised trials with meta...